Epirubicin Hydrochloride

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产品名称: Epirubicin Hydrochloride

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简单介绍

CAS:56390-09-1Formula:C27H29NO11MW:579.98Appearance:Orange-redPowderPurity:95%byHPLC

Epirubicin Hydrochloride 的详细介绍

Cell-permeable. An anthracycline antitumor antibiotic. A stereoisomer of doxorubicin (Cat. No. 1527-5) that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.

Additional Information

Synonyms	(8S-cis)-10-((3-amino-2,3,6-trideoxy-L-arabino-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride; 4'-epiadriamycin; 4'-epidoxorubicin
Product #	E-2306
CAS #	56390-09-1
Chemical Name	(8S-cis)-10-((3-amino-2,3,6-trideoxy-β-L-arabino-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride; 4'-epiadriamycin; 4'-epidoxorubicin
Formula	C₂₇H₂₉NO₁₁
MW	579.98
Appearance	Orange-red Powder
Purity	95% by HPLC
Solubility	Soluble in H₂O (1 mg/ml)
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A cell-permeable Topo II inhibitor used antitumor antibiotic

Additional Information

MDL Number	MFCD00941448
ChemACX	X1026832-3
InChI	InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22-,27-;/m0./s1
SMILES	C[C@H]1[C@@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](Cc3c2c(c4c(c3O)C(=O)c5cccc(c5C4=O)OC)O)(C(=O)CO)O)N)O.Cl

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