Elastatinal, an elastase inhibitor

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产品名称: Elastatinal, an elastase inhibitor

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简单介绍

CAS:51798-45-9Formula:C21H36N8O7MW:512.56Appearance:Yellowtooffwhitepowder

Elastatinal, an elastase inhibitor 的详细介绍

Elastatinal is an elastase inhibitor and has exhibited the ability to inhibit poliovirus and rhinovirus 2A proteinases in vitro. Elastatinal is a tetrapeptide derivative with an aldehyde group which is essential for inhibitory activity. Additionally, it has no effect on DNA repair and UV-induced sister chromatid exchanges, and inhibits the cleavages found at Ala-Ala bonds in peptides that represent the capsid/nucleocapsid site. Elastatinal is an inhibitor of Neutrophil Elastase. In pancreatic tumors Elastatinal has demonstrated the ability to reduce the rate of degradation of endostatin, an angiogenesis inhibitor.

Additional Information

Product #	E-2044
CAS #	51798-45-9
Chemical Name	(2S)-2-[(4S)-2-Amino-1,4,5,6-tetrahydro4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxoethyl-L-glutamamide
Formula	C₂₁H₃₆N₈O₇
MW	512.56
Appearance	Yellow to off white powder
Solubility	Soluble in water upto 20mg/ml
Storage Temp	Store Desiccated at -20°C. Protect from light.
Use	An elastase inhibitor

Additional Information

MDL Number	MFCD00151180
ChemACX	X1089720-8
InChI	InChI=1S/C21H36N8O7/c1-10(2)8-14(19(34)35)28-21(36)29-16(12-6-7-24-20(23)27-12)18(33)26-13(4-5-15(22)31)17(32)25-11(3)9-30/h9-14,16H,4-8H2,1-3H3,(H2,22,31)(H,25,32)(H,26,33)(H,34,35)(H3,23,24,27)(H2,28,29,36)
SMILES	CC(C)CC(C(=O)O)NC(=O)NC(C1CCN=C(N1)N)C(=O)NC(CCC(=O)N)C(=O)NC(C)C=O

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