Doxorubicin

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产品名称: Doxorubicin

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简单介绍

CAS:23214-92-8Formula:C27H29NO11MW:543.5Appearance:OrangeredsolidPurity:>99%byHPLC

Doxorubicin 的详细介绍

*Please inquire the availability for this product. Doxorubicin (adriamycin) is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later approved for human therapeutic use as an antitumor agent for the treatment of a wide range of cancers. Doxorubicin also exhibits anti-HIV and antibacterial activity. The mode of action of doxorubicin is thought to be due to intercalation of DNA and inhibition of nucleic acid synthesis.

Additional Information

Synonyms	Adriamycin, 14-Hydroxydaunomycin, FI 106, K 1039, KW 125, NSC 123127
Product #	D-2539
CAS #	23214-92-8
Formula	C₂₇H₂₉NO₁₁
MW	543.5
Appearance	Orange red solid
Purity	>99% by HPLC
Solubility	Soluble in water (partly), and alcohols
Storage Temp	Room temperature
Therapeutic Area	Oncological Disorders
Use	Doxorubicin is commonly used to treat some leukemias and Hodgkin's lymphoma

Additional Information

MDL Number	MFCD00869292
InChI	InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1
SMILES	C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](Cc3c2c(c4c(c3O)C(=O)c5cccc(c5C4=O)OC)O)(C(=O)CO)O)N)O

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