DMOG, Inhibits prolyl hydroxylase domain-containing proteins

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产品名称: DMOG, Inhibits prolyl hydroxylase domain-containing proteins

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CAS:89464-63-1Formula:C6H9NO5MW:175.14Appearance:Off-whitesolidPurity:99%byTLCNMR(Conforms)

DMOG, Inhibits prolyl hydroxylase domain-containing proteins 的详细介绍

DMOG (89464-63-1) inhibits PHD or prolyl hydroxylase domain-containing proteins, activating HIF1α and inhibiting JMJD2A (IC₅₀ = 2.5 μM). Displays neuroprotective effects. Inhibits neuronal cell death caused by neurotrophin deprivation. DMOG prevents activation of the ATR/CHK1/p53 pathway and suppresses apoptosis induced by DNA damage.

Additional Information

Synonyms	Dimethyloxalylglycine
Product #	D-2637
CAS #	89464-63-1
Chemical Name	N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Formula	C₆H₉NO₅
MW	175.14
Appearance	Off-white solid
Purity	99% by TLC NMR (Conforms)
Solubility	Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Storage Temp	-20°C (des.) Protect from light

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