Davercin

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产品名称: Davercin

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简单介绍

CAS:55224-05-0Formula:C38H65NO14MW:759.9Appearance:WhitesolidPurity:>98%byHPLC

Davercin 的详细介绍

*Please inquire the availability for this product. Davercin (erythromycin A cyclic 11,12-carbonate) is a first generation semi-synthetic erythromycin. Davercin is prepared by coupling the 11- and 12-OH groups to form a cyclic carbonate. This simple modification improves the stability and hydrophobicity of the macrocyclic structure. Davercin shows comparable or better in vitro potency, low host toxicity and improved pharmacokinetics compared with erythromycin.

Additional Information

Synonyms	Erythromycin A 11,12-carbonate, Erythromycin A cyclic 11,12-carbonate, Erythromycin cyclic carbonate
Product #	D-2467
CAS #	55224-05-0
Formula	C38H65NO14
MW	759.9
Appearance	White solid
Purity	>98% by HPLC
Solubility	Soluble in ethanol, methanol, DMF, DMSO Limited water solubility
Storage Temp	-20°C

Additional Information

MDL Number	MFCD01729176
InChI	InChI=1S/C38H65NO14/c1-14-25-38(10)32(52-35(44)53-38)20(4)27(40)18(2)16-36(8,45)31(51-34-28(41)24(39(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-37(9,46-13)30(42)23(7)48-26/h18-26,28-32,34,41-42,45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30+,31?,32-,34+,36-,37-,38-/m1/s1
SMILES	CC[C@@H]1[C@@]2([C@@H]([C@H](C(=O)[C@@H](C[C@@](C([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)C)O)(C)O)C)C)OC(=O)O2)C

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