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Daminozide, KDM2/7 demethylase inhibitor

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产品名称: Daminozide, KDM2/7 demethylase inhibitor
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简单介绍

CAS:1596-84-5Formula:C6H12N2O3MW:160.17Appearance:WhitesolidPurity:98%byTLCNMR(Conforms)


Daminozide, KDM2/7 demethylase inhibitor  的详细介绍

Daminozide (1596-84-5) is a selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50=1.5, 0.55 and 2.1 μM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50> 100 μM.

Additional Information

SynonymsN-(Dimethylamino)succinamic acid
Product #D-2633
CAS #1596-84-5
Chemical Name1-(2,2-Dimethylhydrazide)butanedioic acid
FormulaC6H12N2O3
MW160.17
AppearanceWhite solid
Purity98% by TLC NMR (Conforms)
SolubilitySoluble in DMSO (up to 50 mg/ml), or in Water (up to 20 mg/ml with warming).
Storage TempRT (des.)

Additional Information

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