D4476

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产品名称: D4476

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简单介绍

CAS:301836-43-1Formula:C23H18N4O3MW:398.41Appearance:Off-WhiteSolidPurity:98%byHPLC

D4476 的详细介绍

A cell-permeable, ATP-competitive inhibitor of casein kinase 1 (CK1) (IC= 0.3 M). Also inhibits ALK5 (IC= 0.5 M) and p38MAP kinase (IC= 12 M). Displays selectivity over many other protein kinases.

Additional Information

Synonyms	4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl) -1H-imidazol-2-yl]benzamide
Product #	C-2279
CAS #	301836-43-1
Chemical Name	4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl) -1H-imidazol-2-yl]benzamide
Formula	C₂₃H₁₈N₄O₃
MW	398.41
Appearance	Off-White Solid
Purity	98% by HPLC
Solubility	DMSO (100 mM)
Storage Temp	-20°C
Use	A cell-permeable, ATP-competitive inhibitor of casein kinase 1

Additional Information

MDL Number	MFCD09037526
ChemACX	X1621492-1
InChI	InChI=1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27)
SMILES	c1ccnc(c1)c2c(nc([nH]2)c3ccc(cc3)C(=O)N)c4ccc5c(c4)OCCO5

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