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Cytochalasin D- STRUCTURE-CAS [22144-77-0]

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产品名称: Cytochalasin D- STRUCTURE-CAS [22144-77-0]
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简单介绍

CAS:22144-77-0Formula:C30H37NO6MW:507.63Appearance:WhiteSolidPurity:97%


Cytochalasin D- STRUCTURE-CAS [22144-77-0]  的详细介绍

Cytochalasin D is a cell-permeable fungal toxin, 10-fold more effective than Cytochalasin B.Binds to barbed end of actin filaments, inhibiting the association and dissociation of subunits.

Does not inhibit monosaccharide transport across cell membranes. Cytochalasin D is reported to exhibit antitumor activity, and induce apoptosis.

Additional Information

SynonymsZygosporin A
Product #C-1070
CAS #22144-77-0
Chemical Name(7S,13E,16S,18R,19E,21R)-21-(ACETYLOXY)-7,18-DIHYDROXY-16,18-DIMETHYL-10-PHENYL[11]CYTOCHALASA-6(12),13,19-TRIENE-1,17-DIONE
FormulaC30H37NO6
MW507.63
AppearanceWhite Solid
Purity97%
SolubilitySoluble in 100% ethanol, acetone or ethyl acetate. Insoluble in water.
Melting Point255-260°C
Storage Temp-20°C
UseCytochalasin D is a member of the class of mycotoxins known as cytochalasins

Additional Information

Merck Index12.2859.1996
MDL NumberMFCD00077706
ChemACXX1009686-7
InChIInChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
SMILESC[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3Cc4ccccc4)C)O
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