Cyclosporin D

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产品名称: Cyclosporin D

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简单介绍

CAS:63775-96-2Formula:C63H113N11O12MW:1216.7Appearance:WhitepowderPurity:>95%byHPLC

Cyclosporin D 的详细介绍

*Please inquire the availability for this product. Cyclosporin D is a minor analogue of the cyclosporin family which is only weakly immunologically active. Cyclosporin D is a potent inhibitor of tumor-promoting phorbol esters on mouse skin in vivo, and a potent inhibitor of calcium/calmodulin-dependent EF-2 phosphorylation in vitro.

Additional Information

Synonyms	7-L-valinecyclosporine A
Product #	C-2699
CAS #	63775-96-2
Formula	C63H113N11O12
MW	1216.7
Appearance	White powder
Purity	>95% by HPLC
Solubility	Soluble in 100% ethanol, acetone or ethyl acetate; insoluble in water
Storage Temp	4°C
Use	Cyclosporin D is a metabolite of cyclosporin A

Additional Information

MDL Number	MFCD00907207
InChI	InChI=1S/C63H113N11O12/c1-26-27-41(16)53(76)52-57(80)67-50(39(12)13)62(85)68(19)33-49(75)69(20)44(28-34(2)3)56(79)66-51(40(14)15)63(86)70(21)45(29-35(4)5)55(78)64-42(17)54(77)65-43(18)58(81)71(22)46(30-36(6)7)59(82)72(23)47(31-37(8)9)60(83)73(24)48(32-38(10)11)61(84)74(52)25/h26-27,34-48,50-53,76H,28-33H2,1-25H3,(H,64,78)(H,65,77)(H,66,79)(H,67,80)/b27-26+/t41-,42+,43-,44-,45-,46+,47-,48+,50-,51+,52+,53+/m0/s1
SMILES	C/C=C/[C@H](C)[C@H]([C@@H]1C(=O)N[C@H](C(=O)N(CC(=O)N([C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N([C@@H](C(=O)N([C@H](C(=O)N([C@@H](C(=O)N1C)CC(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)C(C)C)O

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