Cyclosporin B

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产品名称: Cyclosporin B

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简单介绍

CAS:63775-95-1Formula:C61H109N11O12MW:1188.6Appearance:WhitepowderPurity:>97%byHPLC

Cyclosporin B 的详细介绍

*Please inquire the availability for this product. Cyclosporin B is a minor analogue of the cyclosporin complex produced by a number of different fungal genera including Trichoderma, Tolypocladium, Fusarium, Nectria and Acremonium. Cyclosporin B possesses immunosuppressant and antifungal activities but has been much less extensively investigated than the major analogue, cyclosporin A.

Additional Information

Synonyms	7-L-Alaninecyclosporine A
Product #	C-2695
CAS #	63775-95-1
Formula	C61H109N11O12
MW	1188.6
Appearance	White powder
Purity	>97% by HPLC
Solubility	Soluble in chloroform, and methanol
Melting Point	140-143 °C
Storage Temp	-20°C
Therapeutic Area	Autoimmune diseases
Use	Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection

Additional Information

MDL Number	MFCD08062361
InChI	InChI=1S/C61H109N11O12/c1-25-26-27-39(14)51(74)50-55(78)64-41(16)56(79)66(18)32-47(73)67(19)43(28-33(2)3)54(77)65-48(37(10)11)60(83)68(20)44(29-34(4)5)53(76)62-40(15)52(75)63-42(17)57(80)69(21)45(30-35(6)7)58(81)70(22)46(31-36(8)9)59(82)71(23)49(38(12)13)61(84)72(50)24/h25-26,33-46,48-51,74H,27-32H2,1-24H3,(H,62,76)(H,63,75)(H,64,78)(H,65,77)/b26-25+/t39-,40+,41+,42-,43+,44+,45+,46+,48+,49+,50+,51-/m1/s1
SMILES	C/C=C/C[C@@H](C)[C@H]([C@H]1C(=O)N[C@H](C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)C)O

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