Curcumin, Curcuma longa (High Purity)

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产品名称: Curcumin, Curcuma longa (High Purity)

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简单介绍

CAS:458-37-7Formula:C21H20O6MW:368.38Appearance:Orange-yellowSolidPurity:98%

Curcumin, Curcuma longa (High Purity) 的详细介绍

Cell-permeable. An antioxidant and dual inhibitor of 5-lipoxygenase (IC= 8 M)and cyclooxygenase (COX) (IC= 52 M). Also inhibits glutathione S-transferase,induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Also shown to be a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, inhibiting the acetylation of histones H3 and H4 with an ICof ~25 M. Does not affect p300/CREB binding protein-associated factor (PCAF).

Additional Information

Synonyms	1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane
Product #	C-2275
CAS #	458-37-7
Chemical Name	1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane
Formula	C₂₁H₂₀O₆
MW	368.38
Appearance	Orange-yellow Solid
Purity	98%
Solubility	DMSO (25 mg/ml) or EtOH (10 mg/ml)
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	Curcumin (Synthetic), a phenolic pigment originally isolated from Curcuma longa (tumeric) has reported antioxident, anticancer and anti-inflammatory actvities

Additional Information

MDL Number	MFCD00008365
ChemACX	X1001092-3
InChI	InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
SMILES	COc1c(ccc(c1)/C=C/C(=O)CC(=O)/C=C/c2cc(c(cc2)O)OC)O

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