CUDC-101

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产品名称: CUDC-101

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简单介绍

CAS:1012054-59-9Formula:C24H26N4O4MW:434.49Appearance:WhitesolidPurity:≥98%byHPLC

CUDC-101 的详细介绍

A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC₅₀ values of 4.4, 2.4, and 15.7 nM, respectively. Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs.

Additional Information

Product #	C-2274
CAS #	1012054-59-9
Chemical Name	7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide
Formula	C₂₄H₂₆N₄O₄
MW	434.49
Appearance	White solid
Purity	≥98% by HPLC
Solubility	DMSO
Storage Temp	-20°C

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