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Collismycin

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产品名称: Collismycin
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简单介绍

CAS:158792-24-6Formula:C13H13N3O2SMW:275.3Appearance:WhitetooffwhitesolidPurity:>95%byHPLC


Collismycin  的详细介绍

*Please inquire the availability for this product. Collismycin is a rare and unusual antibiotic belonging to the caerulomycin class, containing a core 2,2'-bispyridyl with an oxime substituent, produced by a strain of Streptomyces and discovered by researchers from Kirin, Japan in 1994. Collismycin was discovered as a potent inhibitor of glucocorticoid receptor binding. Collismycin has weak to moderate activity against bacteria, fungi and tumor cell lines. More recently, collismycin has been found to be a potent and selective neuroprotective agent against oxidative stress. Other recent publications have focused on the biosynthesis of collismycin as a route to the production of related analogues.

Additional Information

SynonymsSF 2738A
Product #C-2659
CAS #158792-24-6
FormulaC13H13N3O2S
MW275.3
AppearanceWhite to off white solid
Purity>95% by HPLC
Therapeutic AreaInfectious Diseases
UseCollismycin has activity against bacteria, fungi and tumor cell lines

Additional Information

MDL NumberMFCD00921969
InChIInChI=1S/C13H13N3O2S/c1-18-12-7-10(9-5-3-4-6-14-9)16-11(8-15-17)13(12)19-2/h3-8,17H,1-2H3/b15-8+
SMILESCOc1cc(nc(c1SC)/C=N/O)c2ccccn2
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