c-1401| COCHLIOQUINONE A | CAS 32450-25-2

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产品名称: c-1401| COCHLIOQUINONE A | CAS 32450-25-2

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简单介绍

CAS:32450-25-2Formula:C30H44O8MW:532.67Appearance:YellowLyophilisatePurity:99%byHPLC

c-1401| COCHLIOQUINONE A | CAS 32450-25-2 的详细介绍

Cochlioquinone A is the major component of a bioactive pigment isolated from Bipolaris leersia. Found to be an antagonist of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1).It is anti-angiogenic and exhibits inhibitory activity against diacylglycerol acyltransferase and NADHubiquinone reductase. Newly isolated microbial agent. Demonstrates anti-angiogenic activity. Isolated from Bipolaris zeicola.

Additional Information

Synonyms	Luteoleersin
Product #	C-1401
CAS #	32450-25-2
Chemical Name	(2S,3R,4S)-2-[(3R,4AR,6AR,12S,12AS,12BR)-12-HYDROXY-3-(2-HYDROXY-2-PROPANYL)-6A,12B-DIMETHYL-8,11-DIOXO-1,2,3,4A,5,6,6A,8,11,12,12A,12B-DODECAHYDROPYRANO[3,2-A]XANTHEN-9-YL]-4-METHYL-3-HEXANYL ACETATE
Formula	C₃₀H₄₄O₈
MW	532.67
Appearance	Yellow Lyophilisate
Purity	99% by HPLC
Solubility	Soluble in Methanol; DMSO Soluble in water (60°C, sonification) up to 6mg/ml
Storage Temp	+4°C
Therapeutic Area	Infectious Diseases
Use	Antiangiogenic and nematocidal activities. Antagonist of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1)

Additional Information

MDL Number	MFCD08062299
ChemACX	X2963587-2
InChI	InChI=1S/C30H44O8/c1-9-15(2)25(36-17(4)31)16(3)18-14-19(32)22-24(34)27-29(7)12-10-20(28(5,6)35)37-21(29)11-13-30(27,8)38-26(22)23(18)33/h14-16,20-21,24-25,27,34-35H,9-13H2,1-8H3/t15-,16-,20+,21+,24+,25+,27+,29-,30+/m0/s1
SMILES	CC[C@H](C)[C@H]([C@@H](C)C1=CC(=O)C2=C(C1=O)O[C@@]3(CC[C@@H]4[C@@]([C@H]3[C@@H]2O)(CC[C@@H](O4)C(C)(C)O)C)C)OC(=O)C

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