Clindamycin-2-phosphate

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产品名称: Clindamycin-2-phosphate

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简单介绍

CAS:24729-96-2Formula:C18H34ClN2O8PSMW:505Appearance:WhitesolidPurity:>99%byHPLC

Clindamycin-2-phosphate 的详细介绍

*Please inquire the availability for this product. Clindamycin 2-phosphate is a salt of clindamycin, a semi-synthetic lincosamide. The salt is prepared by selective phosphorylation of the 2-hydroxy moiety of the sugar of clindamycin. The introduction of the phosphate affords improved solubility for injectable formulations. Like other members of the lincosamide family, clindamycin 2-phosphate is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis.

Additional Information

Synonyms	7(S)-Chloro-7-deoxylincomycin 2-phosphate, Cleocin phosphate, Clindamycin phosphate, NSC 618653, U 28508
Product #	C-2651
CAS #	24729-96-2
Formula	C18H34ClN2O8PS
MW	505
Appearance	White solid
Purity	>99% by HPLC
Solubility	Soluble in water, and DMSO
Melting Point	202-204 °C
Storage Temp	4°C
Therapeutic Area	Infectious Diseases
Use	The compound is a potent antibiotic against anaerobic and gram-positive bacteria

Additional Information

MDL Number	MFCD11982855
InChI	InChI=1S/C18H34ClN2O8PS/c1-5-6-10-7-11(21(3)8-10)17(24)20-12(9(2)19)15-13(22)14(23)16(18(28-15)31-4)29-30(25,26)27/h9-16,18,22-23H,5-8H2,1-4H3,(H,20,24)(H2,25,26,27)/t9-,10+,11-,12+,13+,14-,15+,16+,18+/m0/s1
SMILES	CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)OP(=O)(O)O)O)O)[C@H](C)Cl

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