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CHS-828

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产品名称: CHS-828
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简单介绍

CAS:200484-11-3Formula:C19H22ClN5OMW:371.87Appearance:Solid


CHS-828  的详细介绍
NAMPT inhibitor

Additional Information

Product #C-2565
CAS #200484-11-3
FormulaC19 H22 Cl N5 O
MW371.87
AppearanceSolid
SolubilitySoluble in ethanol (~0.5 mg/ml), DMSO (~25 mg/ml), DMF (~25 mg/ml), and 1:2 solution of DMSO:PBS (pH 7.2) (~0.33 mg/ml).
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseGMX1778 (CHS-828) is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) that exhibits a potent anticancer activity

Additional Information

MDL NumberMFCD03700766
ChemACXX1888717-3
InChIInChI=1S/C19H22ClN5O/c20-16-5-7-18(8-6-16)26-14-4-2-1-3-11-23-19(24-15-21)25-17-9-12-22-13-10-17/h5-10,12-13H,1-4,11,14H2,(H2,22,23,24,25)
SMILESc1cc(ccc1OCCCCCC/N=C(NC#N)/Nc2ccncc2)Cl
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