Celecoxib

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产品名称: Celecoxib

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简单介绍

CAS:169590-42-5Formula:C17H14F3N3O2SMW:381.37Appearance:Off-WhiteSolidPurity:99%

Celecoxib 的详细介绍

Celecoxib is a highly selective COX-2 inhibitor and primarily inhibits prostaglandin production. Celecoxib is approximately 7.6-fold more selective for COX-2 inhibition over COX-1.This specificity allows celecoxib to reduce inflammation and pain while minimizing gastrointestinal adverse drug reactions that are common with non-selective non-steroidal anti-inflammatory drugs.

Additional Information

Synonyms	Celebrex, Celebra, Celecox, SC-58635
Product #	C-2263
CAS #	169590-42-5
Chemical Name	4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE
Formula	C₁₇H₁₄F₃N₃O₂S
MW	381.37
Appearance	Off-White Solid
Purity	99%
Solubility	DMSO (200 mg/ml) or EtOH (100 mg/ml)
Melting Point	156-157 °C
Storage Temp	-20°C
Therapeutic Area	Pain / Analgesia
Use	Celecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID)

Additional Information

MDL Number	MFCD00941298
ChemACX	X1353917-4
InChI	InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
SMILES	Cc1ccc(cc1)c2cc(nn2c3ccc(cc3)S(=O)(=O)N)C(F)(F)F

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