Cediranib

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产品名称: Cediranib

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简单介绍

CAS:288383-20-0Formula:C25H27FN4O3MW:450.51Appearance:CrystallineSolidPurity:98%

Cediranib 的详细介绍

Cediranib (AZD2171) is a tyrosine kinase inhibitor that targets vascular endothelial growth factor receptors (VEGFR) 1, 2, and 3, c-KIT, and platelet-derived growth factor receptors. Studies show cediranib to be generally well tolerated as monotherapy at doses of 45 mg/d or less.

Additional Information

Synonyms	AZD2171, Recentin
Product #	C-2261
CAS #	288383-20-0
Chemical Name	4-(4-FLUORO-2-METHYLINDOL-5-YLOXY)-6-METHOXY-7-[3-(PYRROLIDIN-1-YL)PROPOXY]QUINAZOLINE
Formula	C₂₅H₂₇FN₄O₃
MW	450.51
Appearance	Crystalline Solid
Purity	98%
Solubility	DMSO (10 mM)
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	Cediranib (AZD2171) is a tyrosine kinase inhibitor that targets vascular endothelial growth factor receptors (VEGFR) 1, 2, and 3, c-KIT, and platelet-derived growth factor receptors use as anticancer drug

Additional Information

MDL Number	MFCD09954115
ChemACX	X1723155-3
InChI	InChI=1S/C25H27FN4O3/c1-16-12-17-19(29-16)6-7-21(24(17)26)33-25-18-13-22(31-2)23(14-20(18)27-15-28-25)32-11-5-10-30-8-3-4-9-30/h6-7,12-15,29H,3-5,8-11H2,1-2H3
SMILES	CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCC5

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