Caspasr-9 inhibitor Z-LEHD-FMK

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产品名称: Caspasr-9 inhibitor Z-LEHD-FMK

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简单介绍

Formula:C32H43FN6O10MW:690.7Appearance:LiquidPurity:98%byHPLC

Caspasr-9 inhibitor Z-LEHD-FMK 的详细介绍

A synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Additional Information

Synonyms	Caspase-9/Mch6 Inhibitor,Z-LEHD-FMK, Caspase-9 (fluoromethylketone)
Product #	C-2256
Chemical Name	Sequence: Z-Leu-Glu(OMe)-His-Asp(OMe)-FMK (FMK, fluoromethyl ketone).
Formula	C₃₂H₄₃FN₆O₁₀
MW	690.7
Appearance	Liquid
Purity	98% by HPLC
Storage Temp	-20°C

Additional Information

MDL Number	MFCD01862609
ChemACX	X1341207-2
InChI	InChI=1S/C32H43FN6O10/c1-19(2)12-24(39-32(46)49-17-20-8-6-5-7-9-20)30(44)36-22(10-11-27(41)47-3)29(43)38-25(13-21-16-34-18-35-21)31(45)37-23(26(40)15-33)14-28(42)48-4/h5-9,16,18-19,22-25H,10-15,17H2,1-4H3,(H,34,35)(H,36,44)(H,37,45)(H,38,43)(H,39,46)
SMILES	CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2
Peptide Sequence	Z-LEU-GLU(OME)-HIS-ASP(OME)-FMK .TFA

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