Caspase-8 Inhibitor Z-IETD-FMK

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产品名称: Caspase-8 Inhibitor Z-IETD-FMK

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简单介绍

Formula:C30H43FN4O11MW:654.7Appearance:LiquidPurity:>99%byHPLC

Caspase-8 Inhibitor Z-IETD-FMK 的详细介绍

A synthetic peptide that irreversibly inhibits FLICE and related protease/caspase activity and blocks apoptosis. IETD is the specific recognition sequence found in CPP32 proenzyme. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups.)

Additional Information

Synonyms	Z-IETD-FMK, Caspase-8 Inhibitor (fluoromethylketone)
Product #	C-2253
Chemical Name	Z-IETD-FMK, Caspase-8 Inhibitor (fluoromethylketone)
Formula	C₃₀H₄₃FN₄O₁₁
MW	654.7
Appearance	Liquid
Purity	>99% by HPLC
Storage Temp	-20°C

Additional Information

MDL Number	MFCD08461000
ChemACX	X1206331-9
InChI	InChI=1S/C30H43FN4O11/c1-6-17(2)25(35-30(43)46-16-19-10-8-7-9-11-19)28(41)32-20(12-13-23(38)44-4)27(40)34-26(18(3)36)29(42)33-21(22(37)15-31)14-24(39)45-5/h7-11,17-18,20-21,25-26,36H,6,12-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,40)(H,35,43)/t17-,18+,20-,21-,25-,26-/m0/s1
SMILES	CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)OCc1ccccc1
Peptide Sequence	Z-ILE-GLU(O-ME)-THR-ASP(O-ME) FLUOROMETHYL KETONE

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