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Caspase-3 Inhibitor Z-DEVD-FMK

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产品名称: Caspase-3 Inhibitor Z-DEVD-FMK
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简单介绍

Formula:C30H41FN4O12MW:668.7Appearance:LiquidPurity:98%byHPLC


Caspase-3 Inhibitor Z-DEVD-FMK  的详细介绍
A synthetic peptide inhibitor that irreversibly inhibits caspase-3 and related protease/caspase activity and blocks apoptosis. DEVD is the specific recognition sequence found in poly (ADP-ribose) polymerase (PARP). The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Additional Information

SynonymsZ-DEVD-FMK, Caspase-3 inhibitor (fluoromethylketone)
Product #C-2241
Chemical NameSequence: Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK (FMK, fluoromethyl ketone)
FormulaC30H41FN4O12
MW668.7
AppearanceLiquid
Purity98% by HPLC
Storage Temp-20°C

Additional Information

MDL NumberMFCD23380217
ChemACXX1271589-6
InChIInChI=1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1
SMILESCC(C)[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC(=O)OC)NC(=O)OCc1ccccc1
Peptide SequenceZ-ASP(OME)-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE
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