Caspase-1 Inhibitor Z-YVAD-FMK

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产品名称: Caspase-1 Inhibitor Z-YVAD-FMK

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简单介绍

Formula:C31H39FN4O9MW:630.7Appearance:LiquidPurity:99%byHPLC

Caspase-1 Inhibitor Z-YVAD-FMK 的详细介绍

A synthetic peptide that irreversibly inhibits ICE (interleukin-1 converting enzyme, Ki = 0.76 nM) activity. YVAD is the specific recognition sequence for ICE/caspase-1. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Additional Information

Synonyms	Z-YVAD-FMK, Caspase-1 Inhibitor (fluoromethylketone)
Product #	C-2226
Chemical Name	Z-YVAD-FMK, Caspase-1 Inhibitor (fluoromethylketone)
Formula	C₃₁H₃₉FN₄O₉
MW	630.7
Appearance	Liquid
Purity	99% by HPLC
Storage Temp	-20°C

Additional Information

ChemACX	X1271595-4
InChI	InChI=1S/C31H39FN4O9/c1-18(2)27(30(42)33-19(3)28(40)34-23(25(38)16-32)15-26(39)44-4)36-29(41)24(14-20-10-12-22(37)13-11-20)35-31(43)45-17-21-8-6-5-7-9-21/h5-13,18-19,23-24,27,37H,14-17H2,1-4H3,(H,33,42)(H,34,40)(H,35,43)(H,36,41)/t19-,23-,24?,27-/m0/s1
SMILES	CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)OCC2=CC=CC=C2
Peptide Sequence	Z-TYR-VAL-ALA-ASP(OME)-FMK

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