Carbozantinib metastatic castration-resistant prostate cancer, Carbozantinib ca

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产品名称: Carbozantinib metastatic castration-resistant prostate cancer, Carbozantinib ca

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简单介绍

CAS:849217-68-1Formula:C28H24FN3O5MW:501.51Appearance:Off-WhiteSolidPurity:98%byHPLC

Carbozantinib metastatic castration-resistant prostate cancer, Carbozantinib ca 的详细介绍

Cell-permeable. A potent inhibitor of MET, vascular endothelial growth factor receptor 2 (VEGFR2), and RET, with robust antiangiogenic, antitumor, and anti-invasive effects.

Additional Information

Synonyms	N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, Cabometyx TM
Product #	C-2219
CAS #	849217-68-1
Chemical Name	N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Formula	C₂₈H₂₄FN₃O₅
MW	501.51
Appearance	Off-White Solid
Purity	98% by HPLC
Solubility	Soluble in DMSO
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A potent VEGFR2 and Met inhibitor use in cancer

Additional Information

ChemACX	X3528576-0
InChI	InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)
SMILES	COc1cc2c(ccnc2cc1OC)Oc3ccc(cc3)NC(=O)C4(CC4)C(=O)Nc5ccc(cc5)F

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