Candicidin complex

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产品名称: Candicidin complex

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简单介绍

CAS:1403-17-4Formula:C59H84N2O18MW:1109.3Appearance:DullyellowsolidPurity:>95%byHPLC

Candicidin complex 的详细介绍

*Please inquire the availability for this product. Candicidin is a macrocyclic heptaene antifungal complex produced by Streptomyces griseus and isolated by Lechevalier and colleagues in 1953. The candicidin complex comprises analogues A, B, C and D, with candicidin D as the major component. Candicidin is active against fungi, in particular Candida albicans, and is used clinically to treat vaginal candidiasis. Like all polyene antifungal metabolites, candicidin acts by binding to ergosterol and disrupting the fungal membrane.

Additional Information

Synonyms	Levorin
Product #	C-2603
CAS #	1403-17-4
Formula	C₅₉H₈4N₂O₁₈
MW	1109.3
Appearance	Dull yellow solid
Purity	>95% by HPLC
Therapeutic Area	Infectious Diseases
Use	Candicidin is an antifungal compound obtained from Streptomyces griseus. It is active against some fungi including Candida albicans

Additional Information

MDL Number	MFCD01770595
InChI	InChI=1S/C59H84N2O18/c1-35-18-15-13-11-9-7-5-6-8-10-12-14-16-21-47(78-59-56(74)54(61)55(73)38(4)77-59)33-51(71)53(58(75)76)50(70)31-46(67)30-45(66)29-44(65)28-43(64)27-41(62)19-17-20-42(63)32-52(72)79-57(35)37(3)26-36(2)48(68)34-49(69)39-22-24-40(60)25-23-39/h5-16,18,21-25,35-38,43-45,47-48,50-51,53-57,59,64-66,68,70-71,73-74H,17,19-20,26-34,60-61H2,1-4H3,(H,75,76)/b6-5+,9-7+,10-8+,13-11+,14-12+,18-15+,21-16+/t35?,36?,37?,38-,43?,44?,45?,47?,48?,50?,51?,53?,54+,55-,56+,57?,59?/m1/s1
SMILES	C[C@@H]1[C@H]([C@@H]([C@@H](C(O1)OC\2CC(C(C(CC(=O)CC(CC(CC(CC(=O)CCCC(=O)CC(=O)OC(C(/C=C/C=C/C=C/C=C/C=C/C=C/C=C2)C)C(C)CC(C)C(CC(=O)C3=CC=C(C=C3)N)O)O)O)O)O)C(=O)O)O)O)N)O

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