Camptothecin Solution

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产品名称: Camptothecin Solution

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简单介绍

CAS:7689-03-4Formula:C20H16N2O4MW:348.4Appearance:LiquidPurity:98%byTLC

Camptothecin Solution 的详细介绍

Reversibly inhibits nuclear topoisomerase I by binding to and stabilizing the topoisomerase-DNA covalent complex. Inhibits Tat-mediated transcription of HIV-1. Induces apoptosis in Jurkat, osteosarcoma and hepatoma cells.

Additional Information

Synonyms	(S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
Product #	C-2215
CAS #	7689-03-4
Chemical Name	(S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
Formula	C₂₀H₁₆N₂O₄
MW	348.4
Appearance	Liquid
Purity	98% by TLC
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A reversible Mitochondrial Topo I inhibitor shown to exhibit antitumour activity

Additional Information

MDL Number	MFCD00081076
ChemACX	X1009666-5
InChI	InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1
SMILES	CC[C@@]1(c2cc-3n(c(=O)c2COC1=O)Cc4c3nc5ccccc5c4)O

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