Cambinol

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产品名称: Cambinol

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简单介绍

CAS:14513-15-6Formula:C21H16N2O2SMW:360.43Appearance:WhitesolidPurity:≥95%byHPLC

Cambinol 的详细介绍

An inhibitor of NAD-dependent deacetylase activity of human SIRT1 (IC₅₀ = 56 µM) and SIRT2(IC₅₀ = 59 µM). Acts as an antitumor agent. Treatment of BCL6-expressing Burkitt lymphoma cells with Cambinol induces apoptosis accompanied by hyperacetylation of BCL6 and p53.

Additional Information

Product #	C-2214
CAS #	14513-15-6
Chemical Name	5-[(2-hydroxy-5,8-dihydronaphthalen-1-yl)methyl]-6-phenyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; NSC-112546
Formula	C₂₁H₁₆N₂O₂S
MW	360.43
Appearance	White solid
Purity	≥95% by HPLC
Solubility	DMSO (10 mg/ml)
Storage Temp	+4°C

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