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Brefeldin A, BFA

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产品名称: Brefeldin A, BFA
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简单介绍

CAS:20350-15-6Formula:C16H24O4MW:280.4Appearance:WhitePowderPurity:98%


Brefeldin A, BFA  的详细介绍
Berefeldin A is an inhibitor of protein translocation from endoplasmic reticulum (ER) to the Golgi apparatus.Activated Mouse B Cells Lack Expression of Granzyme B

Additional Information

Synonyms1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one; Decumbin; Ascotoxin; γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid λ-lactone; Cyanein; BFA
Product #B-1009
CAS #20350-15-6
Chemical Name1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one
FormulaC16H24O4
MW280.4
AppearanceWhite Powder
Purity98%
SolubilityMeOH
Melting Point204-205°C
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseBFA can induce apoptosis in Neuroendocrine tumor cells by activating caspase-3, and inhibits cell growth by targeting the cell cycle in prostate cancer cells

Additional Information

Merck IndexMerck Index: 12.1393.1996
MDL NumberMFCD12913297
ChemACXX1009661-0
InChIInChI=1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3/b6-4+,8-7+/t11-,12+,13-,14+,15+/m0/s1
SMILESC[C@H]1CCC/C=C/[C@@H]2C[C@@H](C[C@H]2[C@@H](/C=C/C(=O)O1)O)O
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