BIX 01294

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产品名称: BIX 01294

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简单介绍

CAS:935693-62-2Formula:C28H38N6O2MW:490.65Appearance:Off-WhiteSolidPurity:95%byHPLC

BIX 01294 的详细介绍

Selectively impairs the G9a histone lysine methyltransferase (HMTase) and the generation of H3K9me2in vitro. BIX-01294 enables neural progenitor cells (NPCs) to be programmed in the absence of exogenous Oct4.

Additional Information

Synonyms	2-(Hexahydro-4-methyl-1H-1, 4-diazepin-1-yl)-6, 7-dimethoxy-N[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine
Product #	B-1311
CAS #	935693-62-2
Chemical Name	2-(Hexahydro-4-methyl-1H-1, 4-diazepin-1-yl)-6, 7-dimethoxy-N[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine
Formula	C₂₈H₃₈N₆O₂
MW	490.65
Appearance	Off-White Solid
Purity	95% by HPLC
Solubility	DMSO (10 mg/ml) or Ethanol (10 mg/ml)
Storage Temp	Store at +4°C. Protect from air and light. Hygroscopic
Therapeutic Area	Infectious Diseases
Use	Potent G9a and G9a-like protein histone methyltransferase inhibitor use Antimalarial agent

Additional Information

MDL Number	MFCD14560563
ChemACX	X1621488-7
InChI	InChI=1S/C28H38N6O2/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31)
SMILES	CN1CCCN(CC1)c2nc3cc(c(cc3c(n2)NC4CCN(CC4)Cc5ccccc5)OC)OC

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