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ASCOMYCIN STRUCTURE, | CAS [11011-38-4]| Immunosuppressant| Immunomycin, FK520,

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产品名称: ASCOMYCIN STRUCTURE, | CAS [11011-38-4]| Immunosuppressant| Immunomycin, FK520,
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简单介绍

CAS:11011-38-4Formula:C43H69NO12MW:792.0Appearance:WhitePowderPurity:>99.9%


ASCOMYCIN STRUCTURE, | CAS [11011-38-4]| Immunosuppressant| Immunomycin, FK520,  的详细介绍

Ascomycin is an ethyl analog of FK506 with strong immunosuppressant properties. Acts by binding to immunophilins, especially macrophilin-12. It appears that Ascomycin inhibits the production of Th1 (interferon- and IL-2) and Th2 (IL-4 and IL-10) cytokines. Ascomycin acts a calcineurin phosphatase inhibitor (CNPI)1.

 

Additional Information

SynonymsImmunomycin, FK 520, FR 520, FR 900520
Product #A-1258
CAS #11011-38-4
FormulaC43H69NO12
MW792.0
AppearanceWhite Powder
Purity>99.9%
SolubilitySolubility: Soluble in DMSO.
Melting Point163-164‚°C
Storage Temp-20°C, Store in Tightly Sealed Vial.
Product is stable for 3 years as supplied. Ethanol Stock Solutions (1mg/ml) are stable for up to 3 days at -20°C.

Additional Information

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