Ascochlorin

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产品名称: Ascochlorin

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简单介绍

CAS:26166-39-2Formula:C23H29ClO4MW:404.9Appearance:WhitepowderPurity:>98%byHPLC

Ascochlorin 的详细介绍

*Please inquire the availability for this product. Ascochlorin is an antitumor fungal metabolite which specifically inhibits matrix metalloproteinase-9 (MMP-9) activity through suppression of activator protein-1 (AP-1)-dependent induction of MMP-9 gene expression. Via AP-1 suppression, ascochlorin selectively kills MX-1 cells, a human breast cancer cell line lacking estrogen receptors. Ascochlorin also shows activity against Newcastle disease and herpes simplex viruses.

Additional Information

Synonyms	LL-Z 1272 gamma, Ilicicolin D
Product #	A-2633
CAS #	26166-39-2
Formula	C23H29ClO4
MW	404.9
Appearance	White powder
Purity	>98% by HPLC
Solubility	Soluble in ethanol, methanol, DMF, DMSO (09-11 mg/ml), chloroform, and ethyl acetate Insoluble in water
Melting Point	226.87 °C
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	An inhibitor of matrix metalloproteinase-9 activity used as an antiviral and antitumor agent

Additional Information

MDL Number	MFCD01939947
InChI	InChI=1S/C23H29ClO4/c1-13(10-11-23(5)14(2)7-9-19(26)16(23)4)6-8-17-21(27)18(12-25)15(3)20(24)22(17)28/h6,10-12,14,16,27-28H,7-9H2,1-5H3/b11-10+,13-6+/t14-,16+,23+/m1/s1
SMILES	SETVRSKZJJWOPA-FLDGXQSCSA-N

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