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Antimycin complex

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产品名称: Antimycin complex
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简单介绍

CAS:1397-94-0Formula:C28H40N2O9(forA1)MW:548.6(forA1)Appearance:WhitesolidPurity:>95%byHPLC


Antimycin complex  的详细介绍
*Please inquire the availability for this product. Antimycin A is a complex of related macrocyclic lactones, predominantly A1 to A4, isolated from several species of Streptomyces, first reported in the early 1950s for potent antifungal activity. There are over 20 known analogues in the antimycin A class, mostly involving variation of the fatty acid ester chain length or adjacent alkyl starting unit. Antimycin A binds to cytochrome C reductase at the Qi site, inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A is widely used as a bioprobe of respiration and other applications with over 5,000 literature citations.

Additional Information

SynonymsAntipiriculin, Levoristatin, Virosin, Vulgarin
Product #A-2625
CAS #1397-94-0
FormulaC28H40N2O9 (for A1)
MW548.6 (for A1)
AppearanceWhite solid
Purity>95% by HPLC
SolubilitySoluble in 100% ethanol (50 mg/ml) Insoluble in water
Melting Point162-164 °C
Storage Temp-20°C
Therapeutic AreaInfectious Diseases
UseAn antibiotic that induces apoptosis

Additional Information

MDL NumberMFCD01779723
InChIInChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20?,23+,25+/m1/s1
SMILESCCCCCCC1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)c2cccc(c2O)NC=O)C)OC(=O)CC(C)C
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