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Antimycin complex
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产品名称:
Antimycin complex
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简单介绍
CAS:1397-94-0Formula:C28H40N2O9(forA1)MW:548.6(forA1)Appearance:WhitesolidPurity:>95%byHPLC
Antimycin complex
的详细介绍
*Please inquire the availability for this product. Antimycin A is a complex of related macrocyclic lactones, predominantly A1 to A4, isolated from several species of Streptomyces, first reported in the early 1950s for potent antifungal activity. There are over 20 known analogues in the antimycin A class, mostly involving variation of the fatty acid ester chain length or adjacent alkyl starting unit. Antimycin A binds to cytochrome C reductase at the Qi site, inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A is widely used as a bioprobe of respiration and other applications with over 5,000 literature citations.
Additional Information
Synonyms
Antipiriculin, Levoristatin, Virosin, Vulgarin
Product #
A-2625
CAS #
1397-94-0
Formula
C28H40N2O9 (for A1)
MW
548.6 (for A1)
Appearance
White solid
Purity
>95% by HPLC
Solubility
Soluble in 100% ethanol (50 mg/ml) Insoluble in water
Melting Point
162-164 °C
Storage Temp
-20°C
Therapeutic Area
Infectious Diseases
Use
An antibiotic that induces apoptosis
Additional Information
MDL Number
MFCD01779723
InChI
InChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20?,23+,25+/m1/s1
SMILES
CCCCCCC1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)c2cccc(c2O)NC=O)C)OC(=O)CC(C)C
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