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Antimycin A3

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产品名称: Antimycin A3
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简单介绍

CAS:522-70-3Formula:C26H36N2O9MW:520.6Appearance:WhitesolidPurity:>98%byHPLC


Antimycin A3  的详细介绍
*Please inquire the availability for this product. Antimycin A3 is a homologue of the antimycin complex, first isolated in 1958 from Streptomyces blastimyceticus and co-produced with antimycin A4. Antimycin A3 is a more polar analogue of A1 and A2. Like all antimycins, antimycin A3 is a potent inhibitor of respiration by inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A3 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active. Lack of availability of the individual antimycin components has hindered greater understanding of the common and unique molecular targets of the components of the antimycin complex.

Additional Information

SynonymsBlastmycin, NSC 58239
Product #A-2621
CAS #522-70-3
Chemical Name[(2R,3S,6S,7R,8R)-8-BUTYL-3-[(3-FORMAMIDO-2-HYDROXYBENZOYL)AMINO]-2,6-DIMETHYL-4,9-DIOXO-1,5-DIOXONAN-7-YL] 3-METHYLBUTANOATE
FormulaC26H36N2O9
MW520.6
AppearanceWhite solid
Purity>98% by HPLC
Melting Point170 °C
Storage Temp-20°C
Therapeutic AreaInfectious Diseases
UseAntimycin A3 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active

Additional Information

MDL NumberMFCD00869273
InChIInChI=1S/C26H36N2O9/c1-6-7-9-18-23(37-20(30)12-14(2)3)16(5)36-26(34)21(15(4)35-25(18)33)28-24(32)17-10-8-11-19(22(17)31)27-13-29/h8,10-11,13-16,18,21,23,31H,6-7,9,12H2,1-5H3,(H,27,29)(H,28,32)/t15-,16+,18-,21+,23+/m1/s1
SMILESCCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)c2cccc(c2O)NC=O)C)OC(=O)CC(C)C
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