This sterile solution is composed of penicillin (10000-12000 units/ml), streptomycin (10000-12000 ug/ml), and amphotericin B (25-30 ug/ml). The Antibiotic-antimycotic solution works both as an antibacterial and an antifungal. It is effective against both Gram-positive and Gram-negative bacteria as well as yeasts and other fungi. The penicillin works by destroying the cell walls of non-resistant cells by preventing peptidoglycan linkage followed by the triggering of autolysins. Streptomycin disrupts bacterial protein synthesis by binding the ribosomes. Amphotericin B, the anti-fungal element, works by increasing the permeability of the fungal cell membrane by binding ergosterol.
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