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Ansatrienin B
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产品名称:
Ansatrienin B
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简单介绍
CAS:82189-04-6Formula:C36H50N2O8MW:638.8Appearance:PaleyellowpowderPurity:>95%byHPLC(
Ansatrienin B
的详细介绍
*Please inquire the availability for this product. Ansatrienin B, also known as Mycotrienin II and Antibiotic T 23II, was isolated from a Streptomyces sp.. Closely related to the cytotrienins and trienomycins, it displays potent activity against tumor cell lines and inhibits osteoclastic bone resorption. Ansatrienin B also significantly potentiates the action of several clinical anti-cancer agents.
Additional Information
Synonyms
T 23II, Mycotrienin II, T 23II
Product #
A-2617
CAS #
82189-04-6
Chemical Name
(5R,13S,14R,15R)-15,22,24-TRIHYDROXY-5-METHOXY-14,16-DIMETHYL-3-OXO-2-AZABICYCLO[18.3.1]TETRACOSA-1(24),6,8,10,16,20,22-HEPTAEN-13-YL N-(CYCLOHEXYLCARBONYL)-D-ALANINATE
Formula
C36H50N2O8
MW
638.8
Appearance
Pale yellow powder
Purity
>95% by HPLC (< 5% Ansatrienin A)
Solubility
Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO
Storage Temp
-20° C
Therapeutic Area
Musculoskeletal Disorders
Use
It displays potent anticancer activity against cell lines and inhibits osteoclastic bone resorption
Additional Information
MDL Number
MFCD01674355
InChI
InChI=1S/C36H50N2O8/c1-23-14-13-17-27-20-28(39)21-30(34(27)42)38-32(40)22-29(45-4)18-11-6-5-7-12-19-31(24(2)33(23)41)46-36(44)25(3)37-35(43)26-15-9-8-10-16-26/h5-7,11-12,14,18,20-21,24-26,29,31,33,39,41-42H,8-10,13,15-17,19,22H2,1-4H3,(H,37,43)(H,38,40)/b6-5+,12-7+,18-11-,23-14-/t24-,25+,29-,31-,33-/m0/s1
SMILES
C[C@H]1[C@H](C/C=C\C=C/C=C\[C@@H](CC(=O)Nc2cc(cc(c2O)CC/C=C(\[C@@H]1O)/C)O)OC)OC(=O)[C@@H](C)NC(=O)C3CCCCC3
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