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Ansatrienin A
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产品名称:
Ansatrienin A
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简单介绍
CAS:82189-03-5Formula:C36H48N2O8MW:636.8Appearance:YellowPowderPurity:>99%byHPLC
Ansatrienin A
的详细介绍
*Please inquire the availability for this product. Ansatrienin A, isolated from a Streptomyces sp., is closely related to the cytotrienins and trienomycins. It displays potent activity against tumor cell lines and inhibits osteoclastic bone resorption. Ansatrienin A also significantly potentiates the action of several clinical anti-cancer agents.
Additional Information
Synonyms
Mycotrienin I, T 23I
Product #
A-2615
CAS #
82189-03-5
Chemical Name
15-HYDROXY-5-METHOXY-14,16-DIMETHYL-3,22,24-TRIOXO-2-AZABICYCLO[18.3.1]TETRACOSA-1(23),6,8,10,16,20-HEXAEN-13-YL N-(CYCLOHEXYLCARBONYL)-D-ALANINATE
Formula
C36H48N2O8
MW
636.8
Appearance
Yellow Powder
Purity
>99% by HPLC
Solubility
Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO
Storage Temp
-20° C
Therapeutic Area
Musculoskeletal Disorders
Use
An ansamycin antibiotic inhibitor of osteoclastic bone resorption
Additional Information
MDL Number
MFCD01674354
InChI
InChI=1S/C36H48N2O8/c1-23-14-13-17-27-20-28(39)21-30(34(27)42)38-32(40)22-29(45-4)18-11-6-5-7-12-19-31(24(2)33(23)41)46-36(44)25(3)37-35(43)26-15-9-8-10-16-26/h5-7,11-12,14,18,20-21,24-26,29,31,33,41H,8-10,13,15-17,19,22H2,1-4H3,(H,37,43)(H,38,40)/b6-5+,12-7+,18-11+,23-14-/t24?,25-,29?,31?,33?/m1/s1
SMILES
CC1C(C/C=C/C=C/C=C/C(CC(=O)NC2=CC(=O)C=C(C2=O)CC/C=C(\C1O)/C)OC)OC(=O)[C@@H](C)NC(=O)C3CCCCC3
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