AG 1112

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产品名称: AG 1112

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简单介绍

Formula:C15H10N6MW:274.28Appearance:Off-WhitetoYellowSolidPurity:98%

AG 1112 的详细介绍

AG 1112 also known as Tyrphostin AG 1112 is a Casein Kinase II inhibitor. It is a Bcr-Abl Kinase blocker that stimulates and activates the terminal differentiation of K562 cells and the purging of Ph+ cells. AG 1112 has been suggested to be regulatory in function, some of them are cell proliferation, cell differentiation, and apoptosis.

Additional Information

Synonyms	Tyrphostin AG 1112
Product #	A-1176
Chemical Name	(5Z)-3-AMINO-5-[(2Z)-1-CYANO-2-INDOL-3-YLIDENEETHYLIDENE]-1,2-DIHYDROPYRAZOLE-4-CARBONITRILE
Formula	C₁₅H₁₀N₆
MW	274.28
Appearance	Off-White to Yellow Solid
Purity	98%
Solubility	Soluble in DMSO (5mg/ml), acetone or ethyl acetate; insoluble in dichloromethane.
Storage Temp	-20°C

Additional Information

MDL Number	MFCD01868804
InChI	InChI=1S/C15H10N6/c16-6-9(14-12(7-17)15(18)21-20-14)5-10-8-19-13-4-2-1-3-11(10)13/h1-5,8,20-21H,18H2/b10-5+,14-9-
SMILES	C1=CC=C2C(=C1)/C(=C/C(=C/3C(=C(NN3)N)C#N)/C#N)/C=N2

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