Adriamycin Hydrochloride

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产品名称: Adriamycin Hydrochloride

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简单介绍

CAS:25316-40-9Formula:C27H29NO11.ClHMW:579.983Appearance:OrangeRedSolidPurity:99%

Adriamycin Hydrochloride 的详细介绍

Adriamycin is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later approved for human therapeutic used as an anti-tumor agent for the treatment of a wide range of cancers. Adriamycin has also been reported to exhibit anti-HIV and antibacterial activity. The mode of action of Adriamycin is thought to be due to intercalation of DNA and inhibition of nucleic acid synthesis.

Additional Information

Synonyms	Doxorubicin, 14-Hydroxydaunomycin, Adriacin, Adriblastin, Caelyx, Dox, Doxil, Farmiblastina, FI 106, K 1039, KW 125, NSC 123127
Product #	A-1442
CAS #	25316-40-9
Chemical Name	(8S,10S)-10-[(3-AMINO-2,3,6-TRIDEOXY-ALPHA-LYXO-HEXOPYRANOSYL)OXY]-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-5,12-NAPHTHACENEDIONE HYDROCHLORIDE
Formula	C₂₇ H₂₉ N O₁₁ . Cl H
MW	579.983
Appearance	Orange Red Solid
Purity	99%
Solubility	Soluble in water, methanol, DMSO, DMF with moderate ethanol solubility
Melting Point	203.9-205 °C
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	It is used as anticancer agent

Additional Information

MDL Number	MFCD00077757
ChemACX	X1014352-9
InChI	InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
SMILES	C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](Cc3c2c(c4c(c3O)C(=O)c5cccc(c5C4=O)OC)O)(C(=O)CO)O)N)O.Cl

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