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Acarbose

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产品名称: Acarbose
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简单介绍

CAS:56810-94-0Formula:C25H43NO18MW:645.6Appearance:WhitepowderPurity:>95%byHPLC


Acarbose  的详细介绍
Acarbose is pseudo-oligosaccharide with a terminal C7-cyclitol patented in 1975 by Bayer. Acarbose is a component of the amylostatin complex produced by species of Actinoplanes and Streptomyces. Acarbose acts as a potent inhibitor of α-glucosidases and saccharases. Since 1990, acarbose has been used therapeutically for the treatment of type 2 diabetes.

Additional Information

SynonymsAmylostatin J, Bay g 5421, alpha-GHI
Product #A-2581
CAS #56810-94-0
Chemical Name4,6-DIDEOXY-4-([(1S,4R,5S,6S)-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO)-ALPHA-D-GLUCOPYRANOSYL-(1->4)-ALPHA-D-GLUCOPYRANOSYL-(1->4)-D-GLUCOPYRANOSE
FormulaC25H43NO18
MW645.6
AppearanceWhite powder
Purity>95% by HPLC
SolubilitySoluble in water (100 mM), DMSO (100 mM), and methanol
Melting Point165-170 °C
Storage TempRoom temperature
Therapeutic AreaEndocrinological Disorders
UseAcarbose is an a-glucosidase inhibitor.Anti-diabetic drug used to treat type 2 diabetes mellitus

Additional Information

MDL NumberMFCD00869592
InChIInChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
SMILESC[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO
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