Ac-IETD-CHO

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产品名称: Ac-IETD-CHO

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简单介绍

CAS:191338-86-0Formula:C21H34N4O10MW:502.5Appearance:WhiteLyophilizedPowderPurity:97%(HPLC)

Ac-IETD-CHO 的详细介绍

Reversible inhibitor of caspase-8 and granzyme B. It blocks the cleavage of the 32kDa caspase3 precursor into the p12 and p20subunits, thus blocking the formation of active caspase3.lso Inhibits caspase-10. Peptide content is between 70-90%.

Additional Information

Synonyms	Caspase-8 Inhibitor, Caspase-10 Inhibitor , Granzyme B Inhibitor (Aldehyde), Ac-Ile-Glu-Thr-Asp-CHO
Product #	G-1071
CAS #	191338-86-0
Chemical Name	Ac-Ile-Glu-Thr-Asp-CHO
Formula	C₂₁H₃₄N₄O₁₀
MW	502.5
Appearance	White Lyophilized Powder
Purity	97% (HPLC)
Solubility	Soluble in DMSO
Storage Temp	-20°C

Additional Information

MDL Number	MFCD01318858
ChemACX	X1206329-9
InChI	InChI=1S/C21H34N4O10/c1-5-10(2)17(22-12(4)28)20(34)24-14(6-7-15(29)30)19(33)25-18(11(3)27)21(35)23-13(9-26)8-16(31)32/h9-11,13-14,17-18,27H,5-8H2,1-4H3,(H,22,28)(H,23,35)(H,24,34)(H,25,33)(H,29,30)(H,31,32)/t10-,11+,13-,14-,17-,18-/m0/s1
SMILES	CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)C
Peptide Sequence	AC-ILE-GLU-THR-ASP-CHO

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