Ac-ESMD-CHO

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产品名称: Ac-ESMD-CHO

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简单介绍

Formula:C19H30N4O10SMW:506.5Appearance:WhiteLyophilizedPowderPurity:99%(HPLC)

Ac-ESMD-CHO 的详细介绍

Reversible Inhibitor of granzyme B and caspase-8. Inhibits also caspase-6 and -10. This peptide sequence corresponds to one of the cleavage sites of the inactive 32 kDa caspase-3 precursor (aa25-28). Blocks formation of p17 subunit, induces the accumulation of p20 peptide. Peptide content: 70-90%

Additional Information

Synonyms	Caspase-8 Inhibitor, Granzyme B Inhibitor (Aldehyde), Caspase-6, Caspase-10, Ac-Glu-Ser-Met-Asp-CHO
Product #	G-1073
Chemical Name	Ac-Glu-Ser-Met-Asp-CHO
Formula	C₁₉H₃₀N₄O₁₀S
MW	506.5
Appearance	White Lyophilized Powder
Purity	99% (HPLC)
Solubility	Soluble in DMSO
Storage Temp	-20°C

Additional Information

MDL Number	MFCD01318859
ChemACX	X1206330-2
InChI	InChI=1S/C19H30N4O10S/c1-10(26)20-12(3-4-15(27)28)18(32)23-14(9-25)19(33)22-13(5-6-34-2)17(31)21-11(8-24)7-16(29)30/h8,11-14,25H,3-7,9H2,1-2H3,(H,20,26)(H,21,31)(H,22,33)(H,23,32)(H,27,28)(H,29,30)/t11-,12-,13-,14-/m0/s1
SMILES	O=C(N[C@H](C(=O)N[C@H](C=O)CC(=O)O)CCSC)[C@@H](NC(=O)[C@@H](NC(=O)C)CCC(=O)O)CO
Peptide Sequence	AC-GLU-SER-MET-ASP-CHO

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