A23187, Mixed Calcium-Magnesium Salt

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产品名称: A23187, Mixed Calcium-Magnesium Salt

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简单介绍

Formula:C56H66CaN4O12.C56H66MgN4O12MW:2038.69Appearance:WhitePowderPurity:>98%(etOAC:Petroleumether8:2)

A23187, Mixed Calcium-Magnesium Salt 的详细介绍

A23187 has antifungal properties, its antibacterial activities are targeted towards gram positive bacteria. The divalent cation ionophore activity of A23187 is utilized in laborotories to to increase intracellular Ca²⁺ levels in intact cells.A23187 also induces apoptosis in some cells (e.g. mouse lymphoma cell line, or S49, and Jurkat cells) and prevents it in others (e.g. cells dependent on interlukin 3 that have had the factor withdrawn). Used in cell activation experiments when calcium dose-response data are not required. Molar ratio Ca:Mg (1:1).

Additional Information

Product #	A-1128
Chemical Name	BIS[[2-[[(3R,4R,6R,7R,9R,10S)-3,7,9-TRIMETHYL-10-[(1S)-1-METHYL-2-OXO-2-(1H-PYRROL-2-YL)ETHYL]-5,11-DIOXASPIRO[5.5]UNDECAN-4-YL]METHYL]-1,3-BENZOXAZOLE-4-CARBONYL]OXY]CALCIUM; BIS[[2-[[(3R,4R,6R,7R,9R,10S)-3,7,9-TRIMETHYL-10-[(1S)-1-METHYL-2-OXO-2-(1H-PYR
Formula	C₅₆ H₆₆ Ca N₄ O₁₂ . C₅₆ H₆₆ Mg N₄ O₁₂
MW	2038.69
Appearance	White Powder
Purity	>98% (etOAC : Petroleum ether 8:2)
Solubility	Soluble in DMSO, Chloroform, and Ethylacetate.
Melting Point	309 °C
Storage Temp	+4°C
Use	A compound used in cell activation

Additional Information

MDL Number	MFCD00213962
ChemACX	X6952231-2
InChI	InChI=1S/4C28H34N2O6.Ca.Mg/c41-15-10-11-28(17(3)13-16(2)26(36-28)18(4)25(31)20-8-6-12-29-20)35-22(15)14-23-30-24-19(27(32)33)7-5-9-21(24)34-23;;/h45-9,12,15-18,22,26,29H,10-11,13-14H2,1-4H3,(H,32,33);;/q;;;;2+2/p-4/t415-,16-,17-,18-,22-,26+,28-;;/m1111../s1
SMILES	C[C@@H]1CC[C@@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)c3ccc[nH]3)C)C)O[C@@H]1Cc4nc5c(cccc5o4)C(=O)O[Mg]OC(=O)c6cccc7c6nc(o7)C[C@@H]8[C@@H](CC[C@]9(O8)[C@@H](C[C@H]([C@H](O9)[C@H](C)C(=O)c1ccc[nH]1)C)C)C.C[C@@H]1CC[C@@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)

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