A-769662

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产品名称: A-769662

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简单介绍

CAS:844499-71-4Formula:C20H12N2O3SMW:360.39Appearance:CrystallineSolidPurity:98%byHPLC

A-769662 的详细介绍

A-769662 is a Cell-permeable and potent AMPK activator. A-769662 directly stimulates partially purified rat liver AMPK (EC= 0.8 M) and inhibits fatty acid synthesis in primary rat hepatocytes (IC5= 3.2 M).

Additional Information

Synonyms	4-Hydroxy-3-(2-hydroxy-[1,1-biphenyl]-4-yl-)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile
Product #	A-2175
CAS #	844499-71-4
Chemical Name	4-Hydroxy-3-(2’-hydroxy-[1,1’-biphenyl]-4-yl-)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile
Formula	C₂₀H₁₂N₂O₃S
MW	360.39
Appearance	Crystalline Solid
Purity	98% by HPLC
Solubility	DMSO(30 mg/ml) or Ethanol (5 mg/ml)
Melting Point	268.39 °C
Storage Temp	-20°C

Additional Information

MDL Number	MFCD11977269
ChemACX	X1759456-8
InChI	InChI=1S/C20H12N2O3S/c21-9-14-18(24)17-15(10-26-20(17)22-19(14)25)12-7-5-11(6-8-12)13-3-1-2-4-16(13)23/h1-8,10,23H,(H2,22,24,25)
SMILES	C1=CC=C(C(=C1)C2=CC=C(C=C2)C3=CSC4=C3C(=C(C(=O)N4)C#N)O)O

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