9-cis-Retinoic Acid

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产品名称: 9-cis-Retinoic Acid

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简单介绍

CAS:5300-03-8Formula:C20H28O2MW:300.4Appearance:PaleYellowSolidPurity:98%

9-cis-Retinoic Acid 的详细介绍

Product is high affinity ligand for retinoid X receptor (RXR). Able to destablize VDR=RXR heterodimer-DNA complex. Ligand for both the retinoic acid receptor(RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.Attached is a published reference from researchers who have used our 9-cis-RA product.Coordinate Transcriptional Repression of Liver Fatty Acid-binding Protein and Microsomal Triglyceride Transfer Protein Blocks Hepatic Very Low Density Lipoprotein Secretion without Hepatosteatosis.

Additional Information

Product #	R-2002
CAS #	5300-03-8
Chemical Name	(2E,4E,6Z,8E)-3,7-DIMETHYL-9-(2,6,6-TRIMETHYLCYCLOHEXEN-1-YL)NONA-2,4,6,8-TETRAENOIC ACID
Formula	C₂₀H₂₈O₂
MW	300.4
Appearance	Pale Yellow Solid
Purity	98%
Solubility	Soluble in DMSO (25mg/ml), Ethanol (25mg/ml)
Melting Point	190-192°C
Storage Temp	-20°C
Use	9-cis-Retinoic acid is a vitamin A analog that inhibits cell proliferation and induces cell differentiation

Additional Information

MDL Number	MFCD00270072
ChemACX	X1277541-0
InChI	InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
SMILES	CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C

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