7-Oxostaurosporine

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产品名称: 7-Oxostaurosporine

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简单介绍

CAS:141196-69-2Formula:C28H24N4O4MW:480.5Appearance:YellowsolidPurity:>98%byHPLC

7-Oxostaurosporine 的详细介绍

*Please inquire the availability for this product. 7-Oxostaurosporine is the oxidised and highly fluorescent analogue of UCN-01 and UCN-02. 7-Oxostaurosporine is a potent inhibitor of protein kinase C and formation of cellular blebs induced by phorbols. It inhibits the cell cycle at the G2 stage with the accumulation of 4C DNA cells and possesses comparable activity against tumor cells lines to UCN-01. Despite its close relationship to UCN-01 and staurosporine, limited access to the metabolite has restricted a more complete investigation of its properties.

Additional Information

Synonyms	7-Oxostaurosporine, BMY 41950, RK 1409
Product #	O-2563
CAS #	141196-69-2
Formula	C28H24N4O4
MW	480.5
Appearance	Yellow solid
Purity	>98% by HPLC
Solubility	Soluble in DMSO, DMF, ethanol, methanol, and water (limited)
Melting Point	346.61 °C
Storage Temp	-20°C

Additional Information

MDL Number	MFCD14635428
InChI	InChI=1S/C28H24N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,29H,12H2,1-3H3,(H,30,33,34)/t15-,18-,25-,28+/m1/s1
SMILES	O=C5c4c2c3n(c1ccccc12)[C@]8(O[C@@H](n6c3c(c4C(=O)N5)c7ccccc67)C[C@@H](NC)[C@H]8OC)C

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