6BIO , 6-BIO GSK-3 Inhibitor

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产品名称: 6BIO , 6-BIO GSK-3 Inhibitor

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简单介绍

CAS:667463-62-9Formula:C16H10BrN3O2MW:356.2Appearance:DarkredSolidPurity:98%

6BIO , 6-BIO GSK-3 Inhibitor 的详细介绍

Inhibitor of phosphoinositide-dependentn kinase 1 (PDK1). Potent, reversible and ATP-competitive inhibitor of glycogen synthase kinase-3/ (GSK-3/) (IC= 5nM).

Additional Information

Synonyms	[(2'z, 3'e)-6-Bromoindirubin-3'-oxime]
Product #	B-1309
CAS #	667463-62-9
Chemical Name	[(2'z, 3'e)-6-Bromoindirubin-3'-oxime]
Formula	C₁₆H₁₀BrN₃O₂
MW	356.2
Appearance	Dark red Solid
Purity	98%
Solubility	Soluble in DMSO
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A cell-permeable, potent, selective, reversible GSK-3α/β inhibitor in cancer

Additional Information

MDL Number	MFCD08705318
ChemACX	X1543894-7
InChI	InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,18,22H,(H,19,21)/b15-13-,20-14+
SMILES	c1ccc2c(c1)/C(=NO)/C(=C/3c4ccc(cc4NC3=O)Br)/N2

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