14-Hydroxyfilipin (Lagosin)

点击看大图

如果您对该产品感兴趣的话,可以

产品名称: 14-Hydroxyfilipin (Lagosin)

产品型号:

产品展商: 其它品牌

产品文档: 无相关文档

简单介绍

CAS:6834-98-6Formula:C35H58O12MW:670.4Appearance:PaleyellowtotansolidPurity:>95%byHPLC

14-Hydroxyfilipin (Lagosin) 的详细介绍

Lagosin or 14-HYDROXYFILIPIN is a pentaene antifungal antibiotic produced by Streptomyces. It was first isolated in 1958 by researchers at MIT in the USA. Lagosin exhibits broad spectrum antifungal and antitumor activity and, like filipin, acts via interaction with cell membrane sterols.Structurally, lagosin is 14-hydroxyfilipin III and the most polar member of the filipin family of fungicides.

In a recent study 14-HYDROXYFILIPIN was used to evaluate its efficacy on candida albicans biofilm formation. The results revealed that 14-HYDROXYFILIPIN has an inhibitory effect on the formation of C. albicans biofilm in a dose-dependent manner with a minimum inhibitory concentration (MIC) of 10 µg/mL. It also showed that 14-HYDROXYFILIPIN could also induce the apoptosis of C. albicans cells in a dose-dependent manner.

*Please inquire for the availability of this product.

Additional Information

Synonyms	Fungichromin, Lagosin, Cogomycin, Moldcidin B, A246, Pentamycin
Product #	L-2525
CAS #	6834-98-6
Formula	C₃₅H₅₈O₁₂
MW	670.4
Appearance	Pale yellow to tan solid
Purity	>95% by HPLC
Therapeutic Area	Infectious Diseases
Use	Lagosin exhibits broad spectrum antifungal and antitumor activity

Additional Information

MDL Number	MFCD01939601
InChI	InChI=1S/C35H58O12/c1-4-5-11-16-29(41)32-30(42)20-26(38)18-24(36)17-25(37)19-27(39)21-31(43)34(45)33(44)22(2)14-12-9-7-6-8-10-13-15-28(40)23(3)47-35(32)46/h6-10,12-15,23-34,36-45H,4-5,11,16-21H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,22-14+
SMILES	CCCCCC(C1C(CC(CC(CC(CC(CC(C(C(/C(=C/C=C/C=C/C=C/C=C/C(C(OC1=O)C)O)/C)O)O)O)O)O)O)O)O)O

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!