10-Hydroxycamptothecin

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产品名称: 10-Hydroxycamptothecin

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简单介绍

CAS:64439-81-2Formula:C20H16N2O5MW:364.4Appearance:PaleyellowSolidPurity:97%

10-Hydroxycamptothecin 的详细介绍

A DNA topoisomerase I inhibitor. It induces apoptosis in human breast cancer cells.

Product #	H-1132
CAS #	64439-81-2
Chemical Name	(S)-4-Ethyl-4,10- dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2- b]quinoline-3,14(4H,12H)-dione
Formula	C₂₀H₁₆N₂O₅
MW	364.4
Appearance	Pale yellow Solid
Purity	97%
Solubility	Soluble in DMSO
Melting Point	272°C
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A DNA topoisomerase I inhibitor. It induces apoptosis in human breast cancer cells.

MDL Number	MFCD00189425
ChemACX	X7328106-8
InChI	InChI=1S/C20H16N2O5/c1-2-20(26)13-7-15-17-10(6-11-14(21-17)4-3-5-16(11)23)8-22(15)18(24)12(13)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1
SMILES	CC[C@@]1(c2cc-3n(c(=O)c2COC1=O)Cc4c3nc5cccc(c5c4)O)O

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