10'-Desmethoxystreptonigrin

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产品名称: 10'-Desmethoxystreptonigrin

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简单介绍

CAS:136803-89-9Formula:C24H20N4O7MW:476.1Appearance:RedBrownsolidPurity:>95%byHPLC

10'-Desmethoxystreptonigrin 的详细介绍

*Please inquire the availability for this product. 10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumor activity.

Additional Information

Product #	D-2503
CAS #	136803-89-9
Formula	C₂₄H₂₀N₄O₇
MW	476.1
Appearance	Red Brown solid
Purity	>95% by HPLC
Solubility	Soluble in ethanol, methanol, DMF or DMSO
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	10'-desmethoxystreptonigrin have potent and broad spectrum antibacterial and antitumor activity

Additional Information

MDL Number	MFCD01692195
InChI	InChI=1S/C24H20N4O7/c1-9-14(10-5-4-6-13(34-2)20(10)29)15(25)19(28-17(9)24(32)33)12-8-7-11-18(27-12)22(31)16(26)23(35-3)21(11)30/h4-8,28H,25-26H2,1-3H3,(H,32,33)/b14-10+
SMILES	CC\1=C(NC(=C(/C1=C/2\C=CC=C(C2=O)OC)N)c3ccc4c(n3)C(=O)C(=C(C4=O)OC)N)C(=O)O

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