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AGScientific
1-Azakenpaullone
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产品名称:
1-Azakenpaullone
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简单介绍
CAS:676596-65-9Formula:C15H10BrN3OMW:328.2Appearance:Off-whitetotanPowderPurity:95%byHPLC
1-Azakenpaullone
的详细介绍
Analog of kenpaullone acting as a potent and ATP-competitive inhibitor of GSK-3 (IC=18 nM). Displays ~100-200 fold greater selectivity on GSK-3Beta than over CDK1/cyclin B and CDK5/p25 (IC=2.0M and 4.2M, respectively).
Additional Information
Product #
A-1312
CAS #
676596-65-9
Chemical Name
9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one
Formula
C
15
H
10
BrN
3
O
MW
328.2
Appearance
Off-white to tan Powder
Purity
95% by HPLC
Solubility
Soluble in DMSO; insoluble in water.
Storage Temp
-20°C
Additional Information
MDL Number
MFCD09037522
InChI
InChI=1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12)14(10)19-11/h1-6,19H,7H2,(H,18,20)
SMILES
c1cc2c(nc1)-c3c(c4cc(ccc4[nH]3)Br)CC(=O)N2
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