(R,S)-Lenalidomide

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产品名称: (R,S)-Lenalidomide

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简单介绍

CAS:191732-72-6Formula:C13H13N3O3MW:259.26Appearance:Whitetooff-whiteSolidPurity:98%byHPLC

(R,S)-Lenalidomide 的详细介绍

Cell-permeable. An analog of thalidomide that was originally found based on its ability to effectively inhibit tumor necrosis factor production. Lenalidomide is 50,000 times more potent than thalidomide in inhibiting Tumor Necrosis Factor (TNF). Displays potent anti-tumor and anti-inflammatory effects as well as modulates and potentiates host immune responses against multiple myeloma.

Additional Information

Synonyms	(R,S)-3-(4-amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione
Product #	L-2170
CAS #	191732-72-6
Chemical Name	(R,S)-3-(4-amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione
Formula	C₁₃H₁₃N₃O₃
MW	259.26
Appearance	White to off-white Solid
Purity	98% by HPLC
Solubility	DMSO (~100 mg/ml)
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	Lenalidomide is a thalidomide analog known to inhibit TNF-α secretion and possess immunomodulatory properties

Additional Information

MDL Number	MFCD07772307
ChemACX	X1556398-5
InChI	InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
SMILES	c1cc2c(c(c1)N)CN(C2=O)C3CCC(=O)NC3=O

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